Expression pattern of secretory‐cell‐related transcriptional signatures in colon adenocarcinomas defines tumor microenvironment characteristics and correlates with clinical outcomes
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13338
Abstract: Despite the connection of secretory cells to distinct mucus‐containing colon cancer histological subtypes and the interaction of secretory cells with immune cells in the pathogenesis of intestinal inflammatory diseases, whether the secretory cell signatures are… read more here.
Keywords: pattern secretory; secretory cell; tumor microenvironment; secretory ... See more keywords
Efficient secretory production of large‐size heterologous enzymes in Bacillus subtilis: A secretory partner and directed evolution
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27478
Abstract: Secretory production of recombinant proteins provides a simple approach to the production and purification of target proteins in the enzyme industry. We developed a combined strategy for the secretory production of three large‐size heterologous enzymes… read more here.
Keywords: large size; production; secretory; size heterologous ... See more keywords
Immune modulation through secretory autophagy.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30427
Abstract: Autophagy is a central mechanism of cellular homeostasis through the degradation of a wide range of cellular constituents. However, recent evidence suggests that autophagy actively provides information to neighboring cells via a process called secretory… read more here.
Keywords: modulation secretory; secretory; secretory autophagy; homeostasis ... See more keywords
Arp2/3 complex and Mps3 are required for regulation of ribosome biosynthesis in the secretory stress response
Sign Up to like & getrecommendations! Published in 2017 at "Yeast"
DOI: 10.1002/yea.3221
Abstract: Secretory defects cause transcriptional repression of ribosome biogenesis in Saccharomyces cerevisiae. However, the molecular mechanism underlying secretory defect‐induced transcriptional repression of ribosome biogenesis remains to be fully elucidated. In this study, we demonstrated that the… read more here.
Keywords: arp2 complex; complex mps3; response; secretory ... See more keywords
Comparative survey of secretory structures and floral anatomy of Cohniella cepula and Cohniella jonesiana (Orchidaceae: Oncidiinae). New evidences of nectaries and osmophores in the genus
Sign Up to like & getrecommendations! Published in 2018 at "Protoplasma"
DOI: 10.1007/s00709-018-1330-1
Abstract: The morpho-anatomical structure of nectaries, osmophores, and elaiophores, and the anatomical and micromorphological features of floral pieces of Cohniella cepula Hoffmans. and Cohniella jonesiana Rchb.f. were comparatively analyzed. In both species, bracteal and sepal nectaries… read more here.
Keywords: secretory; cohniella; cohniella jonesiana; anatomy ... See more keywords
Effects of aging on the secretory apparatus in the right atrial cardiomyocytes of rats.
Sign Up to like & getrecommendations! Published in 2020 at "Acta histochemica"
DOI: 10.1016/j.acthis.2020.151579
Abstract: The cardiac atria secrets polypeptide hormones usually called natriuretic peptides (NPs). These substances play a relevant role in the blood pressure regulation. The objective of the study was to estimate the effects of aging on… read more here.
Keywords: secretory apparatus; secretory; effects aging; apparatus right ... See more keywords
Efficient production of recombinant Secretory IgA against Clostridium difficile toxins in CHO-K1 cells.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2021.02.013
Abstract: Despite the essential role secretory IgAs play in the defense against pathogenic invasion and the proposed value of recombinant secretory IgAs as novel therapeutics, currently there are no IgA-based therapies in clinics. Secretory IgAs are… read more here.
Keywords: clostridium difficile; secretory; recombinant secretory; difficile toxins ... See more keywords
Mist1 Expression Is Required for Paneth Cell Maturation
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2019.07.003
Abstract: Background Paneth cells are professional secretory cells found within the small intestinal crypt epithelium. Although their role as part of the innate immune complex providing antimicrobial secretory products is well-known, the mechanisms that control secretory… read more here.
Keywords: secretory; paneth cell; expression; mist1 expression ... See more keywords
Autophagy and protein secretion.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.01.015
Abstract: Autophagy - conventional for macroautophagy - is a major recycling strategy that ensures cellular homeostasis through the selective engulfment of cytoplasmic supramolecular cargos in double membrane vesicles and their rapid dispatch to the lysosome for… read more here.
Keywords: autophagy protein; secretion; secretory; protein secretion ... See more keywords
Determination of secretory granule maturation times in pancreatic islet β-cells by serial block face scanning electron microscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2020.107584
Abstract: It is shown how serial block-face electron microscopy (SBEM) of insulin-secreting β-cells in wild-type mouse pancreatic islets of Langerhans can be used to determine maturation times of secretory granules. Although SBEM captures the β -cell… read more here.
Keywords: secretory; microscopy; electron microscopy; serial block ... See more keywords
In situ determination of secretory kinase Fam20C from living cells using fluorescence correlation spectroscopy.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122473
Abstract: Secretory proteins constitute a biologically crucial subset of proteins for regulation of some pathological and physiological processes, and they have become very important biomarkers in clinical diagnosis and therapeutic targets. So far, secretory protein functions… read more here.
Keywords: secretory; fam20c; using fluorescence; spectroscopy ... See more keywords