Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins
Sign Up to like & getrecommendations! Published in 2020 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.0c00325
Abstract: Coibamide A (CbA) is a marine natural product with potent antiproliferative activity against human cancer cells and a unique selectivity profile. Despite promising antitumor activity, the mechanism of cytotoxicity and specific cellular target of CbA… read more here.
Keywords: targets sec61; cba; secretory membrane;
Characterization of Infiltrating Immune Cells and Secretory or Membrane-Associated Proteins in KRAS Lung Adenocarcinoma
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DOI: 10.1155/2023/4987832
Abstract: Background This study identified the expression and prognosis significance of secretory or membrane-associated proteins in KRAS lung adenocarcinoma (LUAD) and depicted the characteristics between the immune cell infiltration and the expression of these genes. Methods… read more here.
Keywords: membrane associated; immune cell; expression; secretory membrane ... See more keywords
Secretory and Membrane-Associated Biomarkers of Mast Cell Activation and Proliferation
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087071
Abstract: Mast cells (MCs) are immune cells distributed in many organs and tissues and involved in the pathogenesis of allergic and inflammatory diseases as a major source of pro-inflammatory and vasoactive mediators. MC-related disorders are heterogeneous… read more here.
Keywords: membrane associated; proliferation; associated biomarkers; secretory membrane ... See more keywords