Molecular details of secretory phospholipase A2 from flax (Linum usitatissimum L.) provide insight into its structure and function
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DOI: 10.1038/s41598-017-10969-9
Abstract: Secretory phospholipase A2 (sPLA2) are low molecular weight proteins (12–18 kDa) involved in a suite of plant cellular processes imparting growth and development. With myriad roles in physiological and biochemical processes in plants, detailed analysis of… read more here.
Keywords: flax; insight structure; phospholipase; molecular details ... See more keywords
Immediate inhibition of spinal secretory phospholipase A2 prevents the pain and elevated spinal neuronal hyperexcitability and neuroimmune regulatory genes that develop with nerve root compression
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DOI: 10.1097/wnr.0000000000001520
Abstract: Cervical nerve root injury induces a host of inflammatory mediators in the spinal cord that initiate and maintain neuronal hyperexcitability and pain. Secretory phospholipase A2 (sPLA2) is an enzyme that has been implicated as a… read more here.
Keywords: secretory phospholipase; spla2; neuronal hyperexcitability; nerve root ... See more keywords
Effects of Statins and Xuezhikang on the Expression of Secretory Phospholipase A2, Group IIA in Rat Vascular Smooth Muscle Cells.
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DOI: 10.1536/ihj.16-163
Abstract: Atherosclerosis is a multifactorial vascular disease characterized by formation of inflammatory lesions. Secretory phospholipase A2, group IIA (sPLA2-IIA) is involved in this process and plays a critical role. However, the exact role of sPLA2-IIA in… read more here.
Keywords: phospholipase group; group iia; expression; secretory phospholipase ... See more keywords
Corosolic Acid Inhibits Secretory Phospholipase A2IIa as an Anti-Inflammatory Function and Exhibits Anti-Tumor Activity in Ehrlich Ascites Carcinoma Bearing Mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s383441
Abstract: Background Inflammation is generally connected to tumour progression and development. The secretory phospholipase A2IIa (sPLA2IIa) is an important inflammatory enzyme that catalyse the hydrolysis of membrane phospholipids into arachidonic and lysophosphatidic acid, which are the… read more here.
Keywords: spla2iia; corosolic acid; anti inflammatory; activity ... See more keywords
Secretory Phospholipase A2 Digital Expression Analysis in Colon Adenocarcinoma
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DOI: 10.21873/invivo.12760
Abstract: Background/Aim: Phospholipases A2 represent a family of enzymes that regulate the metabolism of phospholipids by hydrolyzing them into fatty acids. Secretory phospholipase A2 (SPLA2) catalyzes the calcium-dependent 2-acyl groups hydrolysis to produce 3-sn-phosphoglycerides. This study… read more here.
Keywords: colon adenocarcinoma; secretory phospholipase; spla2; expression ... See more keywords
Secretory Phospholipase A2 and Interleukin-6 Levels as Predictive Markers of the Severity and Outcome of Patients with COVID-19 Infections
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065540
Abstract: Coronavirus disease (COVID-19) has become a global pandemic. COVID-19 patients need immediate diagnosis and rehabilitation, which makes it urgent to identify new protein markers for a prognosis of the severity and outcome of the disease.… read more here.
Keywords: severity outcome; covid infections; secretory phospholipase; patients covid ... See more keywords
Suilyin Disrupts the Blood–Brain Barrier by Activating Group III Secretory Phospholipase A2
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12060919
Abstract: Serious diseases caused by Streptococcus suis serotype 2 (S. suis 2) include septicaemia and meningitis, which are associated with high morbidity and mortality. Proliferation in the blood can result in a breach of the blood–brain… read more here.
Keywords: blood brain; brain barrier; group iii; iii secretory ... See more keywords