Articles with "secretory program" as a keyword



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A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells

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Published in 2022 at "Nature Communications"

DOI: 10.1038/s41467-021-27731-5

Abstract: The GATA4 transcription factor acts as a master regulator of development of multiple tissues. GATA4 also acts in a distinct capacity to control a stress-inducible pro-inflammatory secretory program that is associated with senescence, a potent… read more here.

Keywords: tumor; secretory program; cd8 cells; cytotoxic cd8 ... See more keywords