Functional Diversity of the Excretory/Secretory Proteins of Nematode Parasites.
Sign Up to like & getrecommendations! Published in 2022 at "Acta parasitologica"
DOI: 10.1007/s11686-022-00523-7
Abstract: INTRODUCTION Parasites release a wide array of protein as excretory and secretory products (ESPs). Irrespective of their mode of propagation, ESPs are found to be secreted or excreted by both naturally occurring and laboratory-cultivated parasites.… read more here.
Keywords: diversity; functional diversity; secretory proteins; diversity excretory ... See more keywords
The Toxoplasma Vacuolar H+-ATPase Regulates Intracellular pH and Impacts the Maturation of Essential Secretory Proteins
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.04.038
Abstract: SUMMARY Vacuolar-proton ATPases (V-ATPases) are conserved complexes that couple the hydrolysis of ATP to the pumping of protons across membranes. V-ATPases are known to play diverse roles in cellular physiology. We studied the Toxoplasma gondii… read more here.
Keywords: atpase; atpase regulates; vacuolar atpase; secretory proteins ... See more keywords
Genome-wide identification and comprehensive analysis of Excretory/Secretory proteins in nematodes provide potential drug targets for parasite control.
Sign Up to like & getrecommendations! Published in 2019 at "Genomics"
DOI: 10.1016/j.ygeno.2018.03.007
Abstract: Nematodes are responsible for causing severe diseases in plants, humans and other animals. Infection is associated with the release of Excretory/Secretory (ES) proteins into host cytoplasm and interference with the host immune system which make… read more here.
Keywords: excretory secretory; secretory proteins; targets parasite; identification ... See more keywords
Four thiol-oxidoreductases involved in the formation of disulphide bonds in the Streptomyces lividans TK21 secretory proteins
Sign Up to like & getrecommendations! Published in 2019 at "Microbial Cell Factories"
DOI: 10.1186/s12934-019-1175-0
Abstract: BackgroundBacterial secretory proteins often require the formation of disulphide bonds outside the cell to acquire an active conformation. Thiol-disulphide oxidoreductases are enzymes that catalyse the formation of disulphide bonds. The bacterium Streptomyces lividans is a… read more here.
Keywords: thiol; disulphide; formation disulphide; disulphide bonds ... See more keywords
Review of the Role of Parasitic Nematode Excretory/Secretory Proteins in Host Immunomodulation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Parasitology"
DOI: 10.1645/21-33
Abstract: ABSTRACT Parasitic nematodes infect a variety of organisms including insects and vertebrates. To survive, they evade host immune responses to cause morbidity and mortality. Despite the vast clinical knowledge regarding nematode infections and their biological… read more here.
Keywords: review; excretory secretory; parasitic nematode; host ... See more keywords
Correlation of five secretory proteins with the nasopharyngeal carcinoma metastasis and the clinical applications
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14725
Abstract: In our previous study, five different secretory proteins, including GSN, ADAMTSL4, CALR, PPIA and TXN, have been identified to be associated with the nasopharyngeal carcinoma (NPC) metastasis. In this work, the 5 proteins were further… read more here.
Keywords: npc; adamtsl4 txn; secretory proteins; metastasis ... See more keywords
Cysteine-Rich Secretory Proteins (CRISP) are Key Players in Mammalian Fertilization and Fertility
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DOI: 10.3389/fcell.2021.800351
Abstract: Mammalian fertilization is a complex process involving a series of successive sperm-egg interaction steps mediated by different molecules and mechanisms. Studies carried out during the past 30 years, using a group of proteins named CRISP… read more here.
Keywords: mammalian fertilization; rich secretory; interaction; secretory proteins ... See more keywords
Synthesis of Secretory Proteins in Yarrowia lipolytica: Effect of Combined Stress Factors and Metabolic Load
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073602
Abstract: While overproduction of recombinant secretory proteins (rs-Prots) triggers multiple changes in the physiology of the producer cell, exposure to suboptimal growth conditions may further increase that biological response. The environmental conditions may modulate the efficiency… read more here.
Keywords: cell; stress factors; yarrowia lipolytica; physiology ... See more keywords