Ascorbic acid antagonizes the sedative effect of diazepam possibly through inhibition of GABA(Aρ₁) and GABA(B1) receptors.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2020.66.4.3
Abstract: Gamma-aminobutyric acid (GABA) receptors belong to a ligand-gated ion channels family and are markedly expressed at the axon terminals of retinal bipolar cells. Ascorbic acid (AA), a known and vital antioxidant in the brain can… read more here.
Keywords: gaba receptors; ascorbic acid; sedative effect; gaba ... See more keywords
Zerumbone, a major sesquiterpene from Syringa pinnatifolia Hemsl., exerts the sedative effect by regulating GABAergic nervous system.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.2139/ssrn.4135098
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Zerumbone (ZER) is a humulane sesquiterpenoid isolated from Syringa pinnatifolia Hemsl. (SP), its content accounts for 64.7% of volatile oil and 0.86% of total ethanol extract (TEE), representing one of characteristic ingredient of… read more here.
Keywords: system; syringa pinnatifolia; zer; effect ... See more keywords