Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy
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DOI: 10.1002/2211-5463.13110
Abstract: The propagation of conformational strains by templated seeding is central to the prion concept. Seeded assembly of α‐synuclein into filaments is believed to underlie the prion‐like spreading of protein inclusions in a number of human… read more here.
Keywords: synuclein filaments; seeded assembly; structures synuclein; system atrophy ... See more keywords