Location of the cross‐β structure in prion fibrils: A search by seeding and electron spin resonance spectroscopy
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DOI: 10.1002/pro.4326
Abstract: Prion diseases are transmissible fatal neurodegenerative disorders spreading between humans and other mammals. The pathogenic agent, prion, is a protease‐resistant, β‐sheet‐rich protein aggregate, converted from a membrane protein called PrPC. PrPSc is the misfolded form… read more here.
Keywords: prion; structure; spectroscopy; electron spin ... See more keywords