Prion-Like Seeding of Misfolded α-Synuclein in the Brains of Dementia with Lewy Body Patients in RT-QUIC
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DOI: 10.1007/s12035-017-0624-1
Abstract: The prion-like seeding of misfolded α-synuclein (αSyn) involved in the pathogenesis of Lewy body diseases (LBD) remains poorly understood at the molecular level. Using the real-time quaking-induced conversion (RT-QUIC) seeding assay, we investigated whether brain… read more here.
Keywords: prion like; like seeding; misfolded synuclein; seeding misfolded ... See more keywords