The interaction between transport-segment DNA and topoisomerase IA—crystal structure of MtbTOP1 in complex with both G- and T-segments
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DOI: 10.1093/nar/gkac1205
Abstract: Abstract Each catalytic cycle of type IA topoisomerases has been proposed to comprise multistep reactions. The capture of the transport-segment DNA (T-segment) into the central cavity of the N-terminal toroidal structure is an important action,… read more here.
Keywords: central cavity; segment dna; dna; topoisomerase ... See more keywords