Transcriptional fates of human-specific segmental duplications in brain.
Sign Up to like & getrecommendations! Published in 2018 at "Genome research"
DOI: 10.1101/gr.237610.118
Abstract: Despite the importance of duplicate genes for evolutionary adaptation, accurate gene annotation is often incomplete, incorrect, or lacking in regions of segmental duplication. We developed an approach combining long-read sequencing and hybridization capture to yield… read more here.
Keywords: full length; segmental duplications; specific segmental; human specific ... See more keywords
HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads.
Sign Up to like & getrecommendations! Published in 2020 at "Genome research"
DOI: 10.1101/gr.263566.120
Abstract: Complete and accurate genome assemblies form the basis of most downstream genomic analyses and are of critical importance. Recent genome assembly projects have relied on a combination of noisy long-read sequencing and accurate short-read sequencing,… read more here.
Keywords: accurate; segmental duplications; hicanu; accuracy ... See more keywords