Pregabalin for Recurrent Seizures in Critical Illness: A Promising Adjunctive Therapy, Especially for cyclic Seizures
Sign Up to like & getrecommendations! Published in 2022 at "Neurocritical Care"
DOI: 10.1007/s12028-022-01459-6
Abstract: Pregabalin (PGB) is an effective adjunctive treatment for focal epilepsy and acts by binding to the alpha2-delta subunit of voltage-gated calcium channels to reduce excitatory neurotransmitter release. Limited data exist on its use in the… read more here.
Keywords: seizure burden; recurrent seizures; hourly seizure; cyclic seizures ... See more keywords
Seizure Burden and Neurologic Outcomes After Neonatal Encephalopathy
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DOI: 10.1212/wnl.0000000000207202
Abstract: Background and Objectives Seizures are common during neonatal encephalopathy (NE), but the contribution of seizure burden (SB) to outcomes remains controversial. This study aims to examine the relationship between electrographic SB and neurologic outcomes after… read more here.
Keywords: seizure burden; neurologic outcomes; brain; neonatal encephalopathy ... See more keywords