A randomized phase 2b efficacy study in patients with seizure episodes with a predictable pattern using Staccato® alprazolam for rapid seizure termination
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17441
Abstract: Alprazolam administered via the Staccato® breath‐actuated device is delivered into the deep lung for rapid systemic exposure and is a potential therapy for rapid epileptic seizure termination (REST). We conducted an inpatient study (ENGAGE‐E‐001 [NCT03478982])… read more here.
Keywords: staccato alprazolam; seizure; seizure termination; study ... See more keywords
Progressive Ataxia, Memory Impairments, and Seizure Episodes in Spna2 R1098Q Mouse Variant Affecting Alpha II Spectrin’s Scaffold Stability
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DOI: 10.3390/brainsci13020261
Abstract: SPTAN1 spectrinopathies refer to a group of rare, inherited diseases associated with damage to non-erythrocytic α-II spectrin (α-II). They are linked to a range of mild to severe neuropathologies of the central and peripheral nervous… read more here.
Keywords: spectrin; scaffold stability; progressive ataxia; memory ... See more keywords