High‐frequency oscillations detected in ECoG recordings correlate with cavernous malformation and seizure‐free outcome in a child with focal epilepsy: A case report
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DOI: 10.1002/epi4.12056
Abstract: Epilepsy associated with cavernous malformation (CM) often requires surgical resection of seizure focus to achieve seizure‐free outcome. High‐frequency oscillations (HFOs) in intracranial electroencephalogram (EEG) are reported as potential biomarkers of epileptogenic regions, but to our… read more here.
Keywords: epilepsy; seizure free; report; seizure ... See more keywords
Patient and Caregiver Health State Utilities in Lennox-Gastaut Syndrome and Dravet Syndrome.
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DOI: 10.1016/j.clinthera.2021.09.017
Abstract: PURPOSE Lennox-Gastaut syndrome (LGS) and Dravet syndrome (DS) are rare, treatment-resistant forms of epilepsy characterized by childhood onset of seizures. Cost-effectiveness analysis for new antiseizure medications typically requires health state utilities (HSUs) that reflect the… read more here.
Keywords: caregiver; patient caregiver; free days; seizure free ... See more keywords
Effects of coronavirus disease 2019 vaccination on seizures in patients with epilepsy
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DOI: 10.1097/cm9.0000000000002558
Abstract: Abstract Background: Given that seizures may be triggered by vaccination, this study aimed to evaluate the risk and correlative factors of seizures in patients with epilepsy (PWE) after being vaccinated against coronavirus disease 2019 (COVID-19).… read more here.
Keywords: seizures patients; vaccination; pwe; vaccination seizures ... See more keywords
Personalized prediction model for seizure‐free epilepsy with levetiracetam therapy: a retrospective data analysis using support vector machine
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13720
Abstract: To predict the probability of a seizure‐free (SF) state in patients with epilepsy (PWEs) after treatment with levetiracetam and to identify the clinical and electroencephalographic (EEG) factors that affect outcomes. read more here.
Keywords: model seizure; levetiracetam; seizure free; prediction model ... See more keywords
The challenges of continued antiseizure medicine trials
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DOI: 10.1111/epi.16711
Abstract: To the Editors: We read with interest the letter from Blond et al in a recent issue of Epilepsia discussing seizure freedom with antiseizure medications (ASMs).1 The authors sought to clarify misperceptions of a 2018… read more here.
Keywords: medicine; asm; seizure free; seizure ... See more keywords
Long-term seizure and psychiatric outcomes following laser ablation of mesial temporal structures.
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17183
Abstract: OBJECTIVE Postsurgical seizure outcome following laser interstitial thermal therapy (LiTT) for the management of drug-resistant mesial temporal lobe epilepsy (MTLE) has been limited to 2 years. Furthermore, its impact on presurgical mood and anxiety disorders has… read more here.
Keywords: seizure free; mesial temporal; mood anxiety; following laser ... See more keywords
Seizure-free days as a novel outcome in patients with Lennox-Gastaut syndrome: post hoc analysis of patients receiving cannabidiol in two randomized controlled trials.
Sign Up to like & getrecommendations! Published in 2023 at "Epilepsia"
DOI: 10.1111/epi.17618
Abstract: OBJECTIVE In this post hoc analysis, we aimed to assess seizure-free days as a potential new outcome measure to use in randomized placebo-controlled trials (RCTs) of patients with Lennox-Gastaut syndrome (LGS). METHODS In two phase… read more here.
Keywords: hoc analysis; seizure free; free days; post hoc ... See more keywords
Long term epilepsy outcome dynamics revealed by natural language processing of clinic notes.
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DOI: 10.1111/epi.17633
Abstract: OBJECTIVE Electronic medical records allow for retrospective clinical research with large patient cohorts. However, epilepsy outcomes are often contained in free text notes that are difficult to mine. We recently developed and validated novel natural… read more here.
Keywords: seizure; epilepsy outcome; clinic notes; seizure free ... See more keywords
Recognizing autoimmune encephalitis as a cause of seizures
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DOI: 10.1212/wnl.0000000000007444
Abstract: In this issue of Neurology®, de Bruijn et al.1 report the difference in efficacy between immunotherapy and antiseizure medications (ASMs) in the treatment of seizures secondary to autoimmune encephalitis. Immunotherapy efficacy clearly exceeded that of… read more here.
Keywords: recognizing autoimmune; autoimmune encephalitis; became seizure; seizure free ... See more keywords
Antiseizure Medication Withdrawal in Seizure-Free Patients: Practice Advisory Update Summary
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DOI: 10.1212/wnl.0000000000012944
Abstract: Objective To update a 1996 American Academy of Neurology practice parameter. Methods The authors systematically reviewed literature published from January 1991 to March 2020. Results The long-term (24–60 months) risk of seizure recurrence is possibly… read more here.
Keywords: seizure recurrence; withdrawal; seizure free; seizure ... See more keywords
Relapse After Drug Withdrawal in Patients with Epilepsy After Two Years of Seizure-Free: A Cohort Study
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DOI: 10.2147/ndt.s390280
Abstract: Background and Study Aims Antiepileptic drugs are the first choice of treatment for patients with epilepsy. However, the withdrawal of antiepileptic drugs after seizure-free remains a significant focus for the majority of patients with epilepsy… read more here.
Keywords: patients epilepsy; withdrawal; drug withdrawal; drug ... See more keywords