Subicular Astrocytes Govern Seizure-Impaired Fear Memory.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202510818
Abstract: The mechanisms underlying seizure-associated cognitive impairment remain incompletely characterized. Emerging evidence positions the subiculum, a hippocampal output hub critically involved in both epileptic seizure and cognitive performance, as a putative nexus for this comorbidity. Here,… read more here.
Keywords: memory; subicular astrocytes; fear memory; seizure ... See more keywords
Seizure-induced reduction in glucose utilization promotes brain hypometabolism during epileptogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2018.04.016
Abstract: Brain glucose hypometabolism is an early symptom of acquired epilepsy, its causative mechanism yet unclear. We suggest that a bidirectional positive feedback linking seizures and hypometabolism (hypometabolism induces seizures while seizures disrupt glucose metabolism) may… read more here.
Keywords: epileptogenesis; hypometabolism; seizure induced; glucose metabolism ... See more keywords
Unique features of seizure‐induced cardiorespiratory failure in SS Kcnj16−/− rats: Implications for sudden unexpected death in epilepsy
Sign Up to like & getrecommendations! Published in 2025 at "Epilepsia"
DOI: 10.1111/epi.18360
Abstract: Patients with uncontrolled epilepsy are at high risk for sudden unexpected death in epilepsy (SUDEP), which likely results from a pathological, seizure‐induced disruption of vital physiological systems. The objective of this study was to characterize… read more here.
Keywords: unexpected death; sudden unexpected; seizure induced; death epilepsy ... See more keywords
A seizure-induced T8 burst fracture re-presenting as an acute abdomen
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Case Reports"
DOI: 10.1136/bcr-2017-220346
Abstract: A male aged 44 years presented to the emergency department with a 1-week history of intermittent right-sided abdominal pain radiating to the midline. Examination demonstrated a tender right upper quadrant with voluntary guarding and a low… read more here.
Keywords: fracture presenting; burst fracture; seizure induced; induced burst ... See more keywords
When Apnea Turns Terminal: When, How, Why?
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsy Currents"
DOI: 10.1177/15357597211036815
Abstract: Objective: Sudden unexpected death in epilepsy (SUDEP) is an unpredictable and devastating comorbidity of epilepsy that is believed to be due to cardiorespiratory failure immediately after generalized convulsive seizures. Methods: We performed cardiorespiratory monitoring of… read more here.
Keywords: death; apnea; seizure induced; tonic phase ... See more keywords
5-HT receptors exert differential effects on seizure-induced respiratory arrest in DBA/1 mice
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0304601
Abstract: Both clinical and animal studies demonstrated that seizure-induced respiratory arrest (S-IRA) contributes importantly to sudden unexpected death in epilepsy (SUDEP). It has been shown that enhancing serotonin (5-HT) function relieves S-IRA in animal models of… read more here.
Keywords: dba mice; induced respiratory; dba; respiratory arrest ... See more keywords
Seizure-Induced Spinal Fractures: A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Spine Surgery"
DOI: 10.14444/8244
Abstract: Background Patients with epilepsy have a higher risk of skeletal injuries, and some of these fractures occur in the spine during a seizure. Seizure-induced spinal fractures (SISF) are unusual injuries that typically occur in the… read more here.
Keywords: seizure induced; seizure; induced spinal; review ... See more keywords
Galanin analogs prevent mortality from seizure-induced respiratory arrest in mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2022.901334
Abstract: Objective Sudden Unexpected Death in Epilepsy (SUDEP) accounts for 20% of mortality in those with recurrent seizures. While risk factors, monitoring systems, and standard practices are in place, the pathophysiology of SUDEP is still not… read more here.
Keywords: seizure induced; galanin analogs; galanin; mortality ... See more keywords
Seizure-induced hilar ectopic granule cells in the adult dentate gyrus
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1150283
Abstract: Epilepsy is a chronic neurological disorder characterized by hypersynchronous spontaneous recurrent seizures, and affects approximately 50 million people worldwide. Cumulative evidence has revealed that epileptogenic insult temporarily increases neurogenesis in the hippocampus; however, a fraction… read more here.
Keywords: seizure induced; hilar ectopic; ectopic granule; granule ... See more keywords