Dynamics of convulsive seizure termination and postictal generalized EEG suppression
Sign Up to like & getrecommendations! Published in 2017 at "Brain"
DOI: 10.1093/brain/aww322
Abstract: It is not fully understood how seizures terminate and why some seizures are followed by a period of complete brain activity suppression, postictal generalized EEG suppression. This is clinically relevant as there is a potential… read more here.
Keywords: generalized eeg; suppression; eeg suppression; postictal generalized ... See more keywords
A randomized phase 2b efficacy study in patients with seizure episodes with a predictable pattern using Staccato® alprazolam for rapid seizure termination
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17441
Abstract: Alprazolam administered via the Staccato® breath‐actuated device is delivered into the deep lung for rapid systemic exposure and is a potential therapy for rapid epileptic seizure termination (REST). We conducted an inpatient study (ENGAGE‐E‐001 [NCT03478982])… read more here.
Keywords: staccato alprazolam; seizure; seizure termination; study ... See more keywords