Sirolimus for epileptic seizures associated with focal cortical dysplasia type II
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DOI: 10.1002/acn3.51505
Abstract: To determine whether sirolimus, a mechanistic target of rapamycin (mTOR) inhibitor, reduces epileptic seizures associated with focal cortical dysplasia (FCD) type II. read more here.
Keywords: associated focal; cortical dysplasia; epileptic seizures; seizures associated ... See more keywords
Drug‐resistant seizures associated with hyperinflammatory monocytes in FIRES
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DOI: 10.1002/acn3.51755
Abstract: Therapeutic strategies for patients with febrile infection‐related epilepsy syndrome (FIRES) are limited, ad hoc, and frequently ineffective. Based on evidence that inflammation drives pathogenesis in FIRES, we used ex vivo stimulation of peripheral blood mononuclear… read more here.
Keywords: associated hyperinflammatory; hyperinflammatory monocytes; monocytes fires; drug resistant ... See more keywords
Are seizures associated with neuroschistosomiasis mansoni? An exploratory survey in an endemic area of Brazil.
Sign Up to like & getrecommendations! Published in 2022 at "Transactions of the Royal Society of Tropical Medicine and Hygiene"
DOI: 10.1093/trstmh/trac012
Abstract: BACKGROUND Deposition of Schistosoma mansoni eggs in the brain of patients with hepatosplenic schistosomiasis (HS-SM) is frequent and usually asymptomatic. However, it is questioned whether it could cause seizures. Thus, we investigated the occurrence of… read more here.
Keywords: exploratory survey; neuroschistosomiasis mansoni; survey; mansoni exploratory ... See more keywords
Fenfluramine for seizures associated with Sunflower syndrome.
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DOI: 10.1111/dmcn.14965
Abstract: AIM To determine the efficacy of fenfluramine on seizure frequency in patients with Sunflower syndrome. Secondary endpoints were changes in electroencephalogram (EEG) characteristics, cognitive functioning, executive functioning, and quality of life. METHOD In this open-label… read more here.
Keywords: fenfluramine seizures; sunflower syndrome; fenfluramine; treatment ... See more keywords
Low-intensity exercise combined with sodium valproate attenuates kainic acid-induced seizures and associated co-morbidities by inhibiting NF-κB signaling in mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.993405
Abstract: Sodium valproate (VPA) is a broad-spectrum anticonvulsant that is effective both in adults and children suffering from epilepsy, but it causes psychiatric and behavioral side effects in patients with epilepsy. In addition, 30% of patients… read more here.
Keywords: associated morbidities; intensity exercise; low intensity; seizures associated ... See more keywords