A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A Report of the TASK3-WG1C: Phenotyping Working Group of the ILAE/AES Joint Translational Task Force.
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia open"
DOI: 10.1002/epi4.12676
Abstract: Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes leads to diverse clinical presentation and features. Similarly, animal models of epilepsy arise… read more here.
Keywords: working group; joint translational; task3 wg1c; seizures epilepsy ... See more keywords
Seizures and epilepsy after intracerebral hemorrhage: an update
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DOI: 10.1007/s00415-021-10439-3
Abstract: Seizures are common after intracerebral hemorrhage, occurring in 6–15% of the patients, mostly in the first 72 h. Their incidence reaches 30% when subclinical or non-convulsive seizures are diagnosed by continuous electroencephalogram. Several risk factors… read more here.
Keywords: neurology; hemorrhage update; intracerebral hemorrhage; hemorrhage ... See more keywords
COVID-19, de novo seizures, and epilepsy: a systematic review
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DOI: 10.1007/s10072-020-04932-2
Abstract: We discuss the evidence on the occurrence of de novo seizures in patients with COVID-19, the consequences of this catastrophic disease in people with epilepsy (PWE), and the electroencephalographic (EEG) findings in patients with COVID-19.… read more here.
Keywords: novo seizures; covid novo; systematic review; review ... See more keywords
Cumulative Incidence of Seizures and Epilepsy in Ten-Year-Old Children Born Before 28 Weeks' Gestation.
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DOI: 10.1016/j.pediatrneurol.2017.05.009
Abstract: OBJECTIVE We evaluated the incidence of seizures and epilepsy in the first decade of life among children born extremely premature (less than 28 weeks' gestation). METHOD In a prospective, multicenter, observational study, 889 of 966 eligible… read more here.
Keywords: incidence; weeks gestation; children born; seizures epilepsy ... See more keywords
Neurovascular unit dysfunction as a mechanism of seizures and epilepsy during aging.
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DOI: 10.1111/epi.17210
Abstract: The term neurovascular unit (NVU) describes the structural and functional liaison between specialized brain endothelium, glial and mural cells, and neurons. Within the NVU, the blood-brain barrier (BBB) is the microvascular structure regulating neuronal physiology,… read more here.
Keywords: dysfunction; neurovascular unit; seizures epilepsy; brain ... See more keywords
Hypoparathyroidism Causing Seizures: When Epilepsy Does Not Fit
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DOI: 10.1155/2018/5948254
Abstract: A 24-year-old man presented to the Chris Hani Baragwanath Academic Hospital emergency department with recurrent seizures having previously been diagnosed with epilepsy from age 14. The biochemical investigations and brain imaging were suggestive of seizures… read more here.
Keywords: hypoparathyroidism; causing seizures; hypoparathyroidism causing; seizures epilepsy ... See more keywords
Editors' note: Underestimation of sudden deaths among patients with seizures and epilepsy
Sign Up to like & getrecommendations! Published in 2018 at "Neurology"
DOI: 10.1212/wnl.0000000000005100
Abstract: In “Underestimation of sudden deaths among patients with seizures and epilepsy,” Devinsky et al. aimed to determine the definite and potential frequency of seizures and epilepsy as a cause of death and how often this… read more here.
Keywords: patients seizures; among patients; sudden deaths; seizures epilepsy ... See more keywords
Incidence of Epilepsy and Seizures Over the First 6 Months After a COVID-19 Diagnosis
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DOI: 10.1212/wnl.0000000000201595
Abstract: Background and Objectives The relationship between COVID-19 and epilepsy is uncertain. We studied the potential association between COVID-19 and seizures or epilepsy in the 6 months after infection. Methods We applied validated methods to an… read more here.
Keywords: incidence; infection; seizures epilepsy; compared influenza ... See more keywords
Differential Electrographic Signatures Generated by Mechanistically-Diverse Seizurogenic Compounds in the Larval Zebrafish Brain
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DOI: 10.1523/eneuro.0337-21.2022
Abstract: Abstract We assessed similarities and differences in the electrographic signatures of local field potentials (LFPs) evoked by different pharmacological agents in zebrafish larvae. We then compared and contrasted these characteristics with what is known from… read more here.
Keywords: seizurogenic compounds; frequency; seizures epilepsy; differential electrographic ... See more keywords
Antidepressants drugs for seizures and epilepsy: Where do we stand?
Sign Up to like & getrecommendations! Published in 2022 at "Current neuropharmacology"
DOI: 10.2174/1570159x20666220627160048
Abstract: People with epilepsy (PWE) are more likely to develop depression and both these complex chronic diseases highly affect health-related quality of life (QOL). This comorbidity contributes to the deterioration of the QOL further than increasing… read more here.
Keywords: epilepsy stand; seizures epilepsy; order; drugs seizures ... See more keywords
Beneficial Effects of Statins on Seizures Independent of Their Lipid-Lowering Effect: A Narrative Review
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Medical Sciences"
DOI: 10.30476/ijms.2021.91645.2289
Abstract: Among the many types of central nervous system (CNS) disorders, seizures and epilepsy severely affect the quality of life and routine daily activity of the sufferers. We aimed to review research studies that investigated the… read more here.
Keywords: effect; review; seizures epilepsy; effects statins ... See more keywords