SAT0402 SEL-212 PHASE 2 CLINICAL STUDY IN SYMPTOMATIC GOUT PATIENTS: IMMTOR TOLEROGENIC NANOPARTICLES COMBINED WITH PEGADRICASE MITIGATES IMMUNOGENICITY AND ENABLES SUSTAINED REDUCTION OF SERUM URIC ACID LEVELS, LOW RATE OF GOUT FLARES AND MONTHLY DOSING
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DOI: 10.1136/annrheumdis-2019-eular.7769
Abstract: Background: Pegylated uricases are promising therapies for the treatment of severe chronic gout, but are limited by their immunogenicity. We have previously shown that ImmTOR tolerogenic nanoparticles (formerly known as SVP-Rapamycin) encapsulating rapamycin co-administered with… read more here.
Keywords: biosciences inc; selecta biosciences; gout; gout flares ... See more keywords