Baited SELEX: Drug-Directed Selection of Aptamers to PSMA for In Vivo Targeting of Prostate Cancer Xenografts in Mice.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.5c13307
Abstract: We report a selection strategy for linking a drug-pharmacophore to a degenerate DNA library for use in cell- and whole-animal systematic evolution of ligands by exponential enrichment (SELEX) to direct the selection of aptamers to… read more here.
Keywords: prostate cancer; affinity; drug; selection aptamers ... See more keywords
Rapid selection of aptamers based on protein microarray
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c8ra09232j
Abstract: We report a novel method for the efficient screening of aptamers from a complex ssDNA library based on a microarray chip, which was named Microarray-SELEX. read more here.
Keywords: rapid selection; based protein; selection aptamers; protein microarray ... See more keywords
Automated selection of aptamers against cholangiocarcinoma cells on an integrated microfluidic platform.
Sign Up to like & getrecommendations! Published in 2017 at "Biomicrofluidics"
DOI: 10.1063/1.4991005
Abstract: An integrated microfluidic system capable of automatically identifying aptamers specific to cholangiocarcinoma (CCA) cells was developed herein. The developed system was capable of performing cell-based systematic evolution of ligands via an exponential enrichment (Cell-SELEX) process… read more here.
Keywords: aptamers cholangiocarcinoma; cholangiocarcinoma cells; integrated microfluidic; automated selection ... See more keywords
Review on the Selection of Aptamers and Application in Paper-Based Sensors
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DOI: 10.3390/bios13010039
Abstract: An aptamer is a synthetic oligonucleotide, referring to a single-stranded deoxyribonucleic acid or ribonucleic acid ligand produced by synthesis from outside the body using systematic evolution of ligands by exponential enrichment (SELEX) technology. Owing to… read more here.
Keywords: review selection; aptamers application; selection aptamers; paper based ... See more keywords