Riboswitch identification using Ligase-Assisted Selection for the Enrichment of Responsive Ribozymes (LigASERR)
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DOI: 10.1093/synbio/ysz019
Abstract: Abstract In vitro selection of ligand-responsive ribozymes can identify rare, functional sequences from large libraries. While powerful, key caveats of this approach include lengthy and demanding experimental workflows; unpredictable experimental outcomes and unknown functionality of… read more here.
Keywords: assisted selection; selection; ligase assisted; selection enrichment ... See more keywords