Modeling and simulations to support dose selection for eslicarbazepine acetate therapy in pediatric patients with partial-onset seizures
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DOI: 10.1007/s10928-018-9596-7
Abstract: Modeling and simulations were used to support body weight-based dose selection for eslicarbazepine acetate (ESL) in pediatric subjects aged 4–17 years with partial-onset seizures. A one-compartment pediatric population pharmacokinetic model with formulation-specific first-order absorption, first-order elimination,… read more here.
Keywords: selection eslicarbazepine; dose selection; support; modeling simulations ... See more keywords