Mosaic patterns of selection in genomic regions associated with diverse human traits
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1010494
Abstract: Natural selection shapes the genetic architecture of many human traits. However, the prevalence of different modes of selection on genomic regions associated with variation in traits remains poorly understood. To address this, we developed an… read more here.
Keywords: gwass; selection genomic; regions associated; human traits ... See more keywords
Balancing selection on genomic deletion polymorphisms in humans
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.79111
Abstract: A key question in biology is why genomic variation persists in a population for extended periods. Recent studies have identified examples of genomic deletions that have remained polymorphic in the human lineage for hundreds of… read more here.
Keywords: deletion polymorphisms; selection genomic; balancing selection; polymorphisms humans ... See more keywords