Natural selection of immune and metabolic genes associated with health in two lowland Bolivian populations
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2207544120
Abstract: Significance Humans have adapted to diverse environments, but few studies have linked regions of the genome with evidence of selection to phenotypes. We generated an integrative dataset of genomic, transcriptomic, and biomarker data for the… read more here.
Keywords: selection immune; genes associated; metabolic genes; natural selection ... See more keywords
Positive selection of immune repertoires: A short further history
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DOI: 10.1111/sji.13144
Abstract: The importance of the negative selection of selfâreacting cells from immune repertoires was easily recognized since it would militate against autoimmune disease. However, while the existence of positive selection in the auditioning of newly formed… read more here.
Keywords: negative selection; selection immune; positive selection; immune repertoires ... See more keywords