Selection of RNA‐Cleaving TNA Enzymes for Cellular Mg2+ Imaging
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200651
Abstract: Catalytic DNA‐based fluorescent sensors have enabled cellular imaging of metal ions such as Mg2+. However, natural DNA is prone to nuclease‐mediated degradation. Here, we report the in vitro selection of threose nucleic acid enzymes (TNAzymes) with… read more here.
Keywords: tna enzymes; rna cleaving; enzymes cellular; selection rna ... See more keywords
Highly multiplexed selection of RNA aptamers against a small molecule library
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1101/2022.07.16.500284
Abstract: Applications of synthetic biology spanning human health, industrial bioproduction, and ecosystem monitoring often require small molecule sensing capabilities, typically in the form of genetically encoded small molecule biosensors. Critical to the deployment of greater numbers… read more here.
Keywords: small molecule; selection rna; rna; rna aptamers ... See more keywords
Kin Selection in the RNA World
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DOI: 10.3390/life7040053
Abstract: Various steps in the RNA world required cooperation. Why did life’s first inhabitants, from polymerases to synthetases, cooperate? We develop kin selection models of the RNA world to answer these questions. We develop a very… read more here.
Keywords: rna world; kin selection; cooperation; selection rna ... See more keywords