Examining P‐gp efflux kinetics guided by the BDDCS ‐ Rational selection of in vitro assay designs and mathematical models
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DOI: 10.1016/j.ejps.2019.03.005
Abstract: ABSTRACT The generation of reliable kinetic parameters to describe P‐glycoprotein (P‐gp) activity is essential for predicting the impact of efflux transport on gastrointestinal drug absorption. The compound‐specific selection of in vitro assay designs and ensuing… read more here.
Keywords: assay designs; vitro assay; selection vitro; selection ... See more keywords