Diverse mutant selection windows shape spatial heterogeneity in evolving populations
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DOI: 10.1371/journal.pcbi.1011878
Abstract: Mutant selection windows (MSWs), the range of drug concentrations that select for drug-resistant mutants, have long been used as a model for predicting drug resistance and designing optimal dosing strategies in infectious disease. The canonical… read more here.
Keywords: selection windows; mutant selection; response; drug ... See more keywords