Selective ER-β agonists alleviate neuronal deficits in insulin-resistant estrogen-deficient rats
Sign Up to like & getrecommendations! Published in 2021 at "Climacteric"
DOI: 10.1080/13697137.2020.1857353
Abstract: Abstract Objective The present study aimed to determine the effect of estrogen receptor (ER) agonists on depression and memory impairment in insulin-resistant ovariectomized (OVX) rats. Methods Rats underwent bilateral ovariectomy, and low-dose streptozotocin (STZ) and… read more here.
Keywords: selective agonists; estrogen deficient; insulin resistant; deficits insulin ... See more keywords
Differential effects of selective agonists of neuromedin U1 and U2 receptors in obese and diabetic mice
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14077
Abstract: Neuromedin U (NmU) may be a novel target for obesity treatment owing to its anorectic and energy expenditure enhancing effects. Although two receptors, NMU1 and NMU2, are both responsible for the NmU‐mediated anti‐obesity effects, the… read more here.
Keywords: selective agonists; differential effects; neuromedin receptors; receptors obese ... See more keywords