Improving thermostability of (R)‐selective amine transaminase from Aspergillus terreus through introduction of disulfide bonds
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1572
Abstract: To improve the thermostability of (R)‐selective amine transaminase from Aspergillus terreus (AT‐ATA), we used computer software Disulfide by Design and Modelling of Disulfide Bonds in Proteins to identify mutation sites where the disulfide bonds were… read more here.
Keywords: selective amine; disulfide bonds; thermostability; amine transaminase ... See more keywords
Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-53177-3
Abstract: One of the main factors hampering the implementation in industry of transaminase-based processes for the synthesis of enantiopure amines is their often low storage and operational stability. Our still limited understanding of the inactivation processes… read more here.
Keywords: dimer dissociation; selective amine; amine transaminase; chromobacterium violaceum ... See more keywords