Equine metabolism of the selective androgen receptor modulator YK-11 in urine and plasma following oral administration.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3425
Abstract: YK-11 is a steroidal selective androgen receptor modulator, a compound class prohibited in both equine racing and human sports because of their potentially performance enhancing properties. YK-11 is easily accessible via internet-based supplement vendors making… read more here.
Keywords: metabolism; selective androgen; receptor modulator; androgen receptor ... See more keywords
In-depth metabolic study of non-steroidal selective androgen receptor modulator - GSK2881078 in thoroughbred horses and horse liver microsomes for doping control.
Sign Up to like & getrecommendations! Published in 2023 at "Drug testing and analysis"
DOI: 10.1002/dta.3469
Abstract: Non-steroidal selective androgen receptor modulators (SARMs) are a novel class of compounds that have not yet been clinically approved; however, they appear to have a better anabolic/androgenic ratio than steroids and cause slighter side effects.… read more here.
Keywords: steroidal selective; androgen receptor; non steroidal; selective androgen ... See more keywords
Selective androgen receptor modulator, S42 has anabolic and anti-catabolic effects on cultured myotubes
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2019.01.006
Abstract: We previously identified a novel selective androgen receptor modulator, S42, that does not stimulate prostate growth but has a beneficial effect on lipid metabolism. S42 also increased muscle weight of the levator ani in orchiectomized… read more here.
Keywords: muscle; selective androgen; c2c12 myotubes; modulator s42 ... See more keywords
Overview of the development of selective androgen receptor modulators (SARMs) as pharmacological treatment for osteoporosis (1998-2021).
Sign Up to like & getrecommendations! Published in 2022 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2022.114119
Abstract: Osteoporosis is a common disease in which the risk of fracture increases due to decreased bone mass and qualitative skeletal changes. Selective androgen receptor modulators (SARMs) are agonists with tissue selectivity, which act as partial… read more here.
Keywords: osteoporosis; androgen receptor; receptor modulators; selective androgen ... See more keywords
The forensic response after an adverse analytical finding (doping) involving a selective androgen receptor modulator (SARM) in human athlete.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2021.114433
Abstract: Selective androgen receptor modulators (SARMs) are a class of drugs presenting identical anabolic properties to anabolic steroids in addition to marked reduced androgenic effects. These drugs have emerged in the doping area within the early… read more here.
Keywords: selective androgen; androgen receptor; anti doping; adverse analytical ... See more keywords
In-Sewer Stability Assessment of Anabolic Steroids and Selective Androgen Receptor Modulators.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.1c03047
Abstract: Wastewater-based epidemiology is a potential complementary technique for monitoring the use of performance- and image-enhancing drugs (PIEDs), such as anabolic steroids and selective androgen receptor modulators (SARMs), within the general population. Assessing in-sewer transformation and… read more here.
Keywords: receptor modulators; selective androgen; androgen receptor; steroids selective ... See more keywords
Selective Androgen Receptor Modulator-Induced Liver Injury in Active Duty Male.
Sign Up to like & getrecommendations! Published in 2022 at "Military medicine"
DOI: 10.1093/milmed/usac039
Abstract: Selective androgenic receptor modulators (SARMs) are extensively advertised as safer and more effective analogues to traditional androgenic anabolic steroids, yet there are increasing cases of hepatotoxicity secondary to their use. We present the case of… read more here.
Keywords: active duty; liver injury; selective androgen; receptor ... See more keywords
Selective androgen receptor modulation for muscle weakness in chronic obstructive pulmonary disease: a randomised control trial
Sign Up to like & getrecommendations! Published in 2022 at "Thorax"
DOI: 10.1136/thorax-2021-218360
Abstract: Background Selective androgen receptor modulators (SARMs) increase muscle mass via the androgen receptor. This phase 2A trial investigated the effects of a SARM, GSK2881078, in conjunction with exercise, on leg strength in patients with chronic… read more here.
Keywords: strength; androgen receptor; selective androgen; trial ... See more keywords
Liver injury associated with the use of selective androgen receptor modulators and post-cycle therapy: Two case reports and literature review
Sign Up to like & getrecommendations! Published in 2021 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v9.i16.4062
Abstract: BACKGROUND Muscle growth promoters are being developed for the treatment of disease-induced loss of muscle mass. Ligandrol and ostarine are selective androgen receptor modulators (SARMs) with a non-steroidal structure and a presumably more favorable side… read more here.
Keywords: selective androgen; receptor modulators; post cycle; liver injury ... See more keywords
Selective androgen receptor modulators: the future of androgen therapy?
Sign Up to like & getrecommendations! Published in 2020 at "Translational andrology and urology"
DOI: 10.21037/tau.2019.11.02
Abstract: Selective androgen receptor modulators (SARMs) are small molecule drugs that function as either androgen receptor (AR) agonists or antagonists. Variability in AR regulatory proteins in target tissues permits SARMs to selectively elicit anabolic benefits while… read more here.
Keywords: androgen; selective androgen; receptor modulators; androgen therapy ... See more keywords
Human In Vivo Metabolism and Elimination Behavior of Micro-Dosed Selective Androgen Receptor Modulator RAD140 for Doping Control Purposes
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DOI: 10.3390/metabo12070666
Abstract: RAD140 is a selective androgen receptor modulator which has been abused in sporting competitions. Its use is prohibited by the World Anti-Doping Agency (WADA) for athletes at all times. In addition to its illicit use,… read more here.
Keywords: selective androgen; receptor modulator; rad140 doping; androgen receptor ... See more keywords