Development of an iron-selective antioxidant probe with protective effects on neuronal function
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0189043
Abstract: Iron accumulation, oxidative stress and calcium signaling dysregulation are common pathognomonic signs of several neurodegenerative diseases, including Parkinson´s and Alzheimer’s diseases, Friedreich ataxia and Huntington’s disease. Given their therapeutic potential, the identification of multifunctional compounds… read more here.
Keywords: function; iron selective; selective antioxidant; development iron ... See more keywords
Oxidative Stress Is a Concept, Not an Indication for Selective Antioxidant Treatment
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12061188
Abstract: The steady-state redox status is physiologically important and therefore homeostatically maintained. Changes in the status result in signaling (eustress) or oxidative damage (distress). Oxidative stress (OS) is a hard-to-quantitate term that can be estimated only… read more here.
Keywords: stress; oxidative stress; selective antioxidant; stress concept ... See more keywords