Sign Up to like & get
recommendations!
0
Published in 2018 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.8b00149
Abstract: A series of biaryl chromans exhibiting potent and selective agonism for the GPR40 receptor with positive allosteric modulation of endogenous ligands (AgoPAM) were discovered as potential therapeutics for the treatment of type II diabetes. Optimization…
read more here.
Keywords:
biaryl;
relationship novel;
novel selective;
activity relationship ... See more keywords