Oxidation-induced ortho-selective C–H bond functionalization of 2-naphthylamine derivative
Sign Up to like & getrecommendations! Published in 2018 at "Science China Chemistry"
DOI: 10.1007/s11426-018-9218-5
Abstract: Selective C–H bond functionalization has been emerged as a versatile strategy for the construction of new chemical bonds. In the past decades, the directing group (DG)-assisted C–H bond activation has been developed as one of… read more here.
Keywords: oxidation induced; bond; bond functionalization; selective bond ... See more keywords
Selective CH bond functionalization with engineered heme proteins: new tools to generate complexity.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2018.10.004
Abstract: CH functionalization is an attractive strategy to construct and diversify molecules. Heme proteins, predominantly cytochromes P450, are responsible for an array of CH oxidations in biology. Recent work has coupled concepts from synthetic chemistry, computation,… read more here.
Keywords: complexity; bond; heme proteins; biology ... See more keywords
Catalyst-Controlled Site-Selective Bond Activation.
Sign Up to like & getrecommendations! Published in 2017 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.6b00546
Abstract: One ultimate goal of synthetic chemistry is to install or manipulate any functional group at any position of a molecule. This Account discusses the potential and possible approaches to use catalysis to enable a reaction… read more here.
Keywords: catalyst controlled; controlled site; site selective; chemistry ... See more keywords
Access to Thienopyridine and Thienoquinoline Derivatives via Site-Selective C-H Bond Functionalization and Annulation.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00903
Abstract: To develop of an effective synthetic methodology for biologically relevant thienopyridines, a concise and efficient protocol is described for the synthesis of a series of substituted thienopyridine and thienoquinoline derivatives with high selectivity using EtOCS2K… read more here.
Keywords: site selective; thienoquinoline derivatives; thienopyridine thienoquinoline; selective bond ... See more keywords
Highly Selective C-F Bond Functionalization of Tetrasubstituted gem-Difluoroalkenes and Trisubstituted Monofluoroalkenes Using Grignard Reagents.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01639
Abstract: We herein describe selective C-F bond functionalizations of tetrasubstituted gem-difluoroalkenes and trisubstituted monofluoroalkenes using Grignard reagents without the transition metal catalyst. β,β-Difluoroacrylates react with Grignard reagents under mild conditions to afford tetrasubstituted (E)-β-monofluoroacrylates. Experimental and… read more here.
Keywords: difluoroalkenes trisubstituted; grignard reagents; tetrasubstituted gem; gem difluoroalkenes ... See more keywords
Selective C-O Bond Forming Reactions at Indole-C2-Position toward Polycyclic Indolone or Indolinone Derivatives Tethered with Medium-Sized Rings.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02398
Abstract: A methodology involving the chemoselective synthesis of tetracyclic [1,3]oxazino[3,2-a]indol-4-one or tetracyclic [1,3]oxazino[3,2-a]indoline-4-one tethered with a medium-sized ring by cross dehydrogenative coupling (CDC) or nucleophilic addition (NA) reaction has been developed. [1,3]Oxazino[3,2-a]indol-4-one compounds fused with a… read more here.
Keywords: tethered medium; medium sized; sized ring; medium ... See more keywords
Selective C–C bond formation from rhodium-catalyzed C–H activation reaction of 2-arylpyridines with 3-aryl-2H-azirines† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc05142a
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c8sc05142a
Abstract: A novel method for the synthesis of acylmethyl-substituted 2-arylpyridine derivatives using 3-aryl-2H-azirines was developed. read more here.
Keywords: bond formation; rhodium catalyzed; catalyzed activation; aryl azirines ... See more keywords
Copper-catalysed ortho-selective C-H bond functionalization of phenols and naphthols with α-aryl-α-diazoesters.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc04495d
Abstract: Herein, we reported the first copper-catalyzed highly efficient C(sp2)-H functionalization of unprotected naphthols and phenols with α-aryl-α-diazoesters. In this transformation, CuCl2 efficiently promoted the highly chemo- and site-selective C-H bond functionalization under mild conditions, furnishing… read more here.
Keywords: functionalization; bond functionalization; aryl diazoesters; selective bond ... See more keywords
Selective C–C bond cleavage of oxidized lignin in aqueous phase under mild conditions
Sign Up to like & getrecommendations! Published in 2023 at "Green Chemistry"
DOI: 10.1039/d3gc00496a
Abstract: Selective cleavage of C-C bond in lignin structure is critial for the depolymerization of lignin and producing value-added chemicals. In this study, we reported that Pd/CeO2 catalysts can selectively catalyze... read more here.
Keywords: cleavage; bond cleavage; cleavage oxidized; oxidized lignin ... See more keywords