C4-Selective C-H Borylation of Pyridinium Derivatives Driven by Electron Donor-Acceptor Complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03882
Abstract: The photoinduced C4-selective C-H borylation of pyridines was achieved using electron donor-acceptor complexes derived from a Lewis base and N-amidopyridinium salts under external oxidant- and photocatalyst-free conditions. Notably, the nucleophilic character of phosphite-ligated boryl radicals… read more here.
Keywords: electron donor; donor acceptor; selective borylation; acceptor complexes ... See more keywords
Iridium/Bipyridine-Catalyzed ortho-Selective C-H Borylation of Phenol and Aniline Derivatives.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02936
Abstract: An iridium-catalyzed ortho-selective C-H borylation of phenol and aniline derivatives has been successfully developed. Iridium/bipyridine-catalyzed C-H borylation generally occurred at the meta- and para-positions of aromatic substrates. Introduction of an electron-withdrawing substituent on the bipyridine-type… read more here.
Keywords: catalyzed ortho; borylation; selective borylation; ortho selective ... See more keywords
Hydrogen Bond-Accelerated meta-Selective C–H Borylation of Aromatic Compounds and Expression of Functional Group and Substrate Specificities
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DOI: 10.1021/acscatal.8b05005
Abstract: We found that meta-selective C–H borylation of aromatic compounds was accelerated when using urea moiety-containing bipyridine-type ligands unlike in cases involving a bipyridine-type ligand without the urea moiety. The acceleration was due to the recognition… read more here.
Keywords: aromatic compounds; borylation aromatic; selective borylation; functional group ... See more keywords
meta-Selective C-H Borylation of Benzamides and Pyridines by an Iridium-Lewis Acid Bifunctional Catalyst.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b03138
Abstract: We report herein the iridium-catalyzed meta-selective C-H borylation of benzamides by using a newly designed 2,2'-bipyridine (bpy) ligand bearing an alkylaluminum biphenoxide moiety. We also demonstrate the iridium-catalyzed C3-selective C-H borylation of pyridine with a… read more here.
Keywords: lewis acid; iridium; borylation benzamides; meta selective ... See more keywords
A radical approach for the selective C-H borylation of azines.
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03637-6
Abstract: Boron functional groups are often introduced in place of aromatic carbon-hydrogen bonds to expedite small-molecule diversification through coupling of molecular fragments1-3. Current approaches based on transition metal-catalysed C-H activation are effective for the borylation of… read more here.
Keywords: borylation; borylation azines; radical approach; approach ... See more keywords
Iridium-Catalyzed Site-Selective Borylation of 8-Arylquinolines
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DOI: 10.1055/a-1506-3884
Abstract: We report a convenient method for the highly site selective borylation of 8-arylquinoline. The reaction proceeds smoothly in presence of catalytic amount of [Ir(OMe)(cod)]2 and 2-phenylpyridine derived ligand using bis(pinacolato)diborane as the borylating agent. The… read more here.
Keywords: selective borylation; iridium catalyzed; site selective; catalyzed site ... See more keywords