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   Articles with "selective brain" as a keyword



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Highly selective brain-to-gut communication via genetically defined vagus neurons

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recommendations! Published in 2021 at "Neuron"

DOI: 10.1016/j.neuron.2021.05.004

Abstract: The vagus nerve innervates many organs, and most, if not all, of its motor fibers are cholinergic. However, no one knows its organizing principles-whether or not there are dedicated neurons with restricted targets that act… read more here.

Keywords: highly selective; brain gut; selective brain; via genetically ... See more keywords

Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation.

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recommendations! Published in 2024 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.4c00560

Abstract: Interleukin receptor associated kinase 4 (IRAK4) plays an important role in innate immune signaling through Toll-like and interleukin-1 receptors and represents an attractive target for the treatment of inflammatory diseases and cancer. We previously reported… read more here.

Keywords: potent selective; brain; selective brain; bio ... See more keywords

Rapid selective brain cooling with PolarCap® - a commercial delusion?

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recommendations! Published in 2022 at "Journal of neurotrauma"

DOI: 10.1089/neu.2022.0456

Abstract: The recently published study on external head cooling after concussion in ice hockey players demonstrate a remarkable effect.The scientific basis of the results is, however, ambiguous and the cooling effect of the medical device used… read more here.

Keywords: rapid selective; selective brain; cooling polarcap; commercial delusion ... See more keywords

Author´s reply on "Rapid selective brain cooling with PolarCap® - a commercial delusion?" by Dr. Carl-Henrik Nordström.

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recommendations! Published in 2023 at "Journal of neurotrauma"

DOI: 10.1089/neu.2023.0012

Abstract: The reply posted in text- is an abstract really needed? read more here.

Keywords: rapid selective; author reply; selective brain; cooling polarcap ... See more keywords

Updates on Selective Brain Hypothermia: Studies From Bench Work to Clinical Trials

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recommendations! Published in 2022 at "Frontiers in Neurology"

DOI: 10.3389/fneur.2022.899547

Abstract: Thrombectomy or thrombolysis are the current standards of care for acute ischemic stroke (AIS), however, due to time constraints regarding operations and a multitude of contraindications, AIS remains one of the leading causes of death… read more here.

Keywords: clinical trials; selective brain; brain hypothermia; therapeutic hypothermia ... See more keywords