Copper-catalyzed selective C5-H bromination and difluoromethylation of 8-aminoquinoline amides using ethyl bromodifluoroacetate as the bifunctional reagent
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DOI: 10.1039/d3ra00088e
Abstract: A simple and effective method for the copper-catalyzed selective C5-H bromination and difluoromethylation of 8-aminoquinoline amides with ethyl bromodifluoroacetate as the bifunctional reagent was developed. The combination of cupric catalyst and alkaline additive results in… read more here.
Keywords: difluoromethylation; bromination difluoromethylation; bromination; copper catalyzed ... See more keywords
Selective α-bromination of aryl carbonyl compounds: prospects and challenges
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DOI: 10.1080/00397911.2019.1668415
Abstract: Abstract The α-bromination of carbonyl compounds is one of the most important transformations and also important precursors in synthetic organic chemistry. Particularly, the side chain monobromination of carbonyl compounds has been a challenging task, because… read more here.
Keywords: bromination aryl; selective bromination; carbonyl compounds; aryl carbonyl ... See more keywords