Selective chemical tracking of Dnmt1 catalytic activity in live cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Cell"
DOI: 10.1016/j.molcel.2022.02.008
Abstract: Summary Enzymatic methylation of cytosine to 5-methylcytosine in DNA is a fundamental epigenetic mechanism involved in mammalian development and disease. DNA methylation is brought about by collective action of three AdoMet-dependent DNA methyltransferases, whose catalytic… read more here.
Keywords: dna; dnmt1 catalytic; chemical tracking; selective chemical ... See more keywords
Selective Chemical Modulation of Interlayer Excitons in Atomically Thin Heterostructures.
Sign Up to like & getrecommendations! Published in 2020 at "Nano letters"
DOI: 10.1021/acs.nanolett.9b05254
Abstract: Strongly-bound interlayer excitons (XIs) in atomically thin transition metal dichalcogenide (TMDC) heterostructures such as MoS2/WSe2 show promising optoelectronic properties for spinvalleytronics and excitonic devices. The ability to probe and control XIs is critical for the… read more here.
Keywords: interlayer excitons; modulation interlayer; interlayer; chemical modulation ... See more keywords
Dibenzocyclooctendiones (DBCDOs): Arginine-Selective Chemical Labeling Reagents Obtained through Benzilic Acid Rearrangement.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01970
Abstract: We demonstrate that dibenzocyclooctendiones (DBCDOs) are efficient chemical reagents for the site-specific labeling of arginine-containing biomolecules. Unlike the commonly used probes, DBCDOs undergo an irreversible ring-contracted rearrangement with the guanidinium group on arginine residues under… read more here.
Keywords: selective chemical; arginine selective; dbcdos arginine; dibenzocyclooctendiones dbcdos ... See more keywords
Fabrication of nanostructured silicon surface using selective chemical etching
Sign Up to like & getrecommendations! Published in 2017 at "Technical Physics"
DOI: 10.1134/s106378421711024x
Abstract: A two-stage process based on selective chemical etching induced by metal nanoclusters is used to fabricate nanostructured surfaces of silicon plates with a relatively low reflectance. At silicon surfaces covered with silver nanoclusters, the SERS… read more here.
Keywords: fabrication nanostructured; silicon surface; nanostructured silicon; chemical etching ... See more keywords
nSite-Selective, Chemical Modification of Protein at Aromatic Side Chain and Their Emergent Applications.
Sign Up to like & getrecommendations! Published in 2021 at "Protein and peptide letters"
DOI: 10.2174/0929866528666210129152535
Abstract: Site-selective chemical modification of protein side chain has probed enormous opportunities in the fundamental understanding of cellular biology and therapeutic applications. Primarily, in the field of biopharmaceutical where formulation of bioconjugates is found to be… read more here.
Keywords: aromatic side; side chain; chemical modification; selective chemical ... See more keywords
Selective Chemical Labeling and Sequencing of 5-Hydroxymethylcytosine in DNA at Single-Base Resolution
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.749211
Abstract: 5-Hydroxymethylcytosine (5hmC), the oxidative product of 5-methylcytosine (5mC) catalyzed by ten-eleven translocation enzymes, plays an important role in many biological processes as an epigenetic mediator. Prior studies have shown that 5hmC can be selectively labeled… read more here.
Keywords: dna; single base; base resolution; selective chemical ... See more keywords