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Published in 2019 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-019-02910-3
Abstract: Objectives To compare selective COX-2 inhibitors with ibuprofen in terms of analgesia, rescue medication consumption, and adverse effects after impacted third molar removal. Materials and methods Electronic databases were searched. Single dose, double-blind, randomized, and…
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Keywords:
selective cox;
cox inhibitors;
third molar;
molar removal ... See more keywords
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Published in 2022 at "Drug Research"
DOI: 10.1055/a-1727-5733
Abstract: Aim Enflicoxib, a selective COX-2 inhibitor approved for the treatment of pain and inflammation associated with osteoarthritis in dogs (Daxocox ® [Ecuphar/Animalcare Group]) was assessed for its genotoxic potential in a battery of in vitro…
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Keywords:
vitro;
genotoxic potential;
vivo;
battery vitro ... See more keywords
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Published in 2019 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2018.1502687
Abstract: Abstract A series of 26 selective COX-2 inhibitors which reported previously by our laboratory was selected to generate three-dimensional quantitative structure activity relationship (3D-QSAR) model. Active conformation of each molecule was predicted by docking studies…
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Keywords:
comfa comfa;
selective cox;
comfa;
cox inhibitors ... See more keywords
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Published in 2019 at "Expert Opinion on Therapeutic Patents"
DOI: 10.1080/13543776.2019.1623880
Abstract: ABSTRACT Introduction: COX-2 is a key enzyme in the process of prostaglandins (PGs) synthesis. The products of this enzyme could play a major role as the mediators of the inflammatory response and some other medical…
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Keywords:
selective cox;
anticancer agents;
cox inhibitors;
cox ... See more keywords
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Published in 2019 at "Europace"
DOI: 10.1093/europace/euy180
Abstract: Abstract Aims Non-steroidal anti-inflammatory drugs (NSAIDs), particularly selective COX-2 inhibitors, are associated with an increased risk of cardiovascular adverse events. However, the association between these drugs and out-of-hospital cardiac arrest with electrocardiogram-documented ventricular tachycardia/ventricular fibrillation…
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Keywords:
selective cox;
cox inhibitors;
study;
case ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179809
Abstract: Objective Hepatopulmonary syndrome (HPS) is characterized by hypoxia in patients with chronic liver disease. The mechanism of HPS includes pulmonary vasodilatation, inflammation, and angiogenesis. Prostaglandins synthesized by cyclooxygenases (COX) participate in vascular responsiveness, inflammation and…
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Keywords:
hepatopulmonary syndrome;
selective cox;
inhibition;
inflammation ... See more keywords