Trans-selective cyclizations of alpha-bromocarboxamides and E/Z-mixed internal olefins catalyzed by a Fe salt.
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DOI: 10.1039/d2cc04796a
Abstract: There are several reports of lactam cyclizations, but most yield less-substituted lactam rings. Therefore, diastereoselective cyclization to yield highly substituted lactams is one of the challenges in this field. We therefore propose a strategy involving… read more here.
Keywords: selective cyclizations; alpha bromocarboxamides; internal olefins; trans selective ... See more keywords