Prospective computational design and in vitro bio-analytical tests of new chemical entities as potential selective CYP17A1 lyase inhibitors.
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DOI: 10.1016/j.bioorg.2019.103462
Abstract: The development and advancement of prostate cancer (PCa) into stage 4, where it metastasize, is a major problem mostly in elder males. The growth of PCa cells is stirred up by androgens and androgen receptor… read more here.
Keywords: new chemical; selective cyp17a1; prospective computational; chemical entities ... See more keywords