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Selective depletion of plasma cells in vivo based on the specificity of their secreted antibodies

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1 Published in 2019 at "European Journal of Immunology"

DOI: 10.1002/eji.201948144

Abstract: Antibody‐mediated diseases affect more than 10% of the human population. For most, no cure is available, particularly when the pathogenic antibodies are secreted by long‐lived plasma cells resistant to conventional immunosuppressive therapies. Current therapeutic approaches… read more here.

Keywords: depletion plasma; plasma cells; antibody; selective depletion ... See more keywords

Selective Depletion of Adult GFAP-Expressing Tanycytes Leads to Hypogonadotropic Hypogonadism in Males

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1 Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.869019

Abstract: In adult mammals, neural stem cells are localized in three neurogenic regions, the subventricular zone of the lateral ventricle (SVZ), the subgranular zone of the dentate gyrus of the hippocampus (SGZ) and the hypothalamus. In… read more here.

Keywords: gfap expressing; selective depletion; gfap; expressing tanycytes ... See more keywords

Selective depletion of naïve T cells by targeting CD45RA

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1 Published in 2023 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.1009143

Abstract: COPYRIGHT © 2023 Naik and Triplett. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the… read more here.

Keywords: cells targeting; depletion cells; targeting cd45ra; selective depletion ... See more keywords