Ag-Catalyzed selective fluorination of 6-substituted 2-amionpyrazines
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2018.12.003
Abstract: Abstract The fluorination of 6-substituted 2-aminopyrazines with Selectfluor in the presence of Ag2CO3 is established under mild conditions. This method selectively produced the fluorinated 2-aminopyrazine derivatives in fair to high yield. The regioselectivity of this… read more here.
Keywords: fluorination substituted; substituted amionpyrazines; chemistry; fluorination ... See more keywords
Selective Fluorination of 4-Substituted 2-Aminopyridines and Pyridin-2(1 H)-ones in Aqueous Solution.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b02003
Abstract: Fluorination of 2-aminopyridines and pyridin-2(1 H)-ones in the presence of Selectfluor, water, and chloroform under mild conditions has been realized. This method gives fluorinated pyridines in good to high yields with high regioselectivities. The electron-deficient… read more here.
Keywords: selective fluorination; aminopyridines pyridin; pyridin ones; fluorination ... See more keywords