Production of enantiopure β-amino-γ-hydroxyesters from benzoic acid by a selective formal aminohydroxylation
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DOI: 10.1016/j.tetlet.2017.04.048
Abstract: The enantioselective preparation of three protected β-amino-γ-hydroxyesters from benzoic acid is described. The employed synthetic methodology involves the ipso, ortho cis-dihydroxylation of benzoic acid by the mutant strain Ralstonia eutropha B9, followed by a selective… read more here.
Keywords: hydroxyesters benzoic; selective formal; amino hydroxyesters; benzoic acid ... See more keywords
Photo- and Cu(I)-Promoted Branched-Selective Formal Hydroacylation of Terminal Alkynes via the Intermolecular Coupling of Siloxycarbenes with Alkyne–Cu Complexes
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DOI: 10.1093/chemle/upaf084
Abstract: A photoinduced and copper-promoted coupling reaction of alkanoylsilanes and terminal acetylenes, which affords the corresponding α, β-enones in branched-selective manner, the formal hydroacylation products, has been developed. The established coupling is expected to proceed via… read more here.
Keywords: photo promoted; hydroacylation; formal hydroacylation; selective formal ... See more keywords