Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia.
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DOI: 10.1021/acs.jmedchem.1c01296
Abstract: Galectin-3 is a β-galactoside-specific, carbohydrate-recognizing protein (lectin) that is strongly implicated in cancer development, metastasis, and drug resistance. Galectin-3 promotes migration and ability to withstand drug treatment of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells.… read more here.
Keywords: acute lymphoblastic; novel selective; galectin; lymphoblastic leukemia ... See more keywords