In silico designing of domain B selective gyrase inhibitors for effective treatment of resistant tuberculosis.
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DOI: 10.1016/j.tube.2018.08.005
Abstract: One of the major mechanisms followed by the therapeutic agents to target the causative organism of TB, Mycobacterium tuberculosis, involves disruption of its DNA replication cycle. The process of replication involves two steps, i.e., breakage… read more here.
Keywords: selective gyrase; gyrase inhibitors; gyrb domain; tuberculosis ... See more keywords