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Neuroprotective effect of monophosphoryl lipid A, a detoxified lipid A derivative, in photothrombotic model of unilateral selective hippocampal ischemia in rat

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Published in 2018 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2018.02.045

Abstract: HighlightsPhotothrombotic model of unilateral selective hippocampal ischemia caused learning and memory deficit.Immunologic preconditioning with MPL and LPS resulted in rehabilitation of damaged learning and memory function.Following immunological preconditioning, TLR4 receptor reprogramming protects against cerebral ischemic… read more here.

Keywords: selective hippocampal; model unilateral; ischemia; mpl ... See more keywords