Selective Hydrofunctionalization of Alkenyl Fluorides Enabled by Nickel-Catalyzed Hydrogen Atoms and Group Transfer: Reaction Development and Mechanistic Study.
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DOI: 10.1021/jacs.4c01506
Abstract: Due to the unique effect of fluorine atoms, the efficient construction of high-value alkyl fluorides has attracted significant interest in modern drug development. However, enantioselective catalytic strategies for the efficient assembly of highly functionalized chiral… read more here.
Keywords: reaction; development; alkenyl fluorides; nickel catalyzed ... See more keywords
Metal-catalyzed Markovnikov-type selective hydrofunctionalization of terminal alkynes.
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DOI: 10.1039/d4cs00167b
Abstract: Metal-catalyzed highly Markovnikov-type selective hydrofunctionalization of terminal alkynes provides a straightforward and atom-economical route to access 1,1-disubstituted alkenes, which have a wide range of applications in organic synthesis. However, the highly Markovnikov-type selective transformations are… read more here.
Keywords: metal catalyzed; type selective; markovnikov type; selective hydrofunctionalization ... See more keywords