C3 Selective Hydroxylation of Pyridines via Photochemical Valence Isomerization of Pyridine N-Oxides.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c10057
Abstract: The C-H hydroxylation of the pyridine C3 position is a highly desirable transformation but remains a great challenge due to the inherent electronic properties of this heterocycle core which bring difficulties in chemical reactivity and… read more here.
Keywords: pyridine; selective hydroxylation; pyridines via; hydroxylation pyridines ... See more keywords
para-Selective hydroxylation of alkyl aryl ethers.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc06210g
Abstract: para-Selective hydroxylation of alkyl aryl ethers is established, which proceeds with a ruthenium(II) catalyst, hypervalent iodine(III) and trifluoroacetic anhydride via a radical mechanism. This protocol tolerates a wide scope of substrates and provides a facile… read more here.
Keywords: aryl ethers; hydroxylation alkyl; para selective; selective hydroxylation ... See more keywords
Selective hydroxylation of naphthalene using the H2O2-dependent engineered P450BM3 driven by dual-functional small molecules
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Porphyrins and Phthalocyanines"
DOI: 10.1142/s108842461850061x
Abstract: We herein report the H2O2-dependent selective hydroxylation of naphthalene catalyzed by engineered P450BM3 with the assistance of dual-functional small molecules (DFSMs). The mutation at position 268 significantly improved the hydroxylation activity of P450BM3, which is… read more here.
Keywords: hydroxylation; h2o2 dependent; dual functional; engineered p450bm3 ... See more keywords