Selective Iron-Catalyzed Deaminative Hydrogenation of Amides
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DOI: 10.1021/acs.organomet.6b00816
Abstract: The five-coordinate iron(II) hydride complex (iPrPNP)Fe(H)CO (iPrPNP = N[CH2CH2(PiPr2)]2) was found to selectively catalyze deaminative hydrogenation of amides to the corresponding amines and primary alcohols. It is one of the most active amide hydrogenation catalysts… read more here.
Keywords: hydrogenation; hydrogenation amides; iron catalyzed; deaminative hydrogenation ... See more keywords
Redox-Selective Iron Catalysis for α-Amino C-H Bond Functionalization via Aerobic Oxidation.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03542
Abstract: Single-electron oxidation and α-deprotonation of tertiary anilines using Fe(phen)3(PF6)3 afford α-aminoalkyl radicals, which can be coupled with electrophilic partners to afford various tetrahydroquinolines. Mechanistically, the Fe(phen)n2+/3+ catalytic cycle is maintained by O2 or a TBHP… read more here.
Keywords: iron catalysis; oxidation; redox selective; iron ... See more keywords
Selective Iron-Mediated C- and O-Addition of Phenolic Nucleophiles to a Cyclohexadiene Scaffold Using Renewable Precursors
Sign Up to like & getrecommendations! Published in 2019 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.9b00127
Abstract: Renewable phenols have been investigated as nucleophiles for the addition to a cationic cyclohexadienyl iron carbonyl scaffold. Benign conditions compatible with solvents such as ethanol and water were developed, and for the first time, selective… read more here.
Keywords: addition; mediated addition; selective iron; addition phenolic ... See more keywords