Highly Selective β-Mannosylations and β-Rhamnosylations Catalyzed by a Bis-thiourea.
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DOI: 10.1021/jacs.0c04255
Abstract: We report highly β-selective bis-thiourea-catalyzed 1,2-cis-O-pyranosylations employing easily accessible acetonide-protected donors. A wide variety of alcohol nucleophiles, including complex natural products, glycosides, and amino acids were β-mannosylated and rhamnosylated successfully using an operationally simple protocol… read more here.
Keywords: highly selective; selective mannosylations; bis thiourea; mannosylations rhamnosylations ... See more keywords